Six months have passed since Dr Ogden moved to Buffalo and Det Murdoch is constantly a loggerheads with Dr Francis, her replacement While Insp Brackenreid thinks highly of Francis, who was recruited from Scotland Yard, Murdoch finds him stubborn and unimaginative He also seems to be in no rush to help Murdoch with his latest case where human body body parts were discovered on a riverbank encased in cement A homeless man living in the woods nearby is questioned and released and Murdoch corresponds with Dr Ogden who offers him valuable advice in her letters He also gets help from a retired detective, Malcolm Lamb Murdoch connects his current investigation a rape and murder that had occurred many years before
故事以现代东京为背景在也门担任无国界外科医生目前归国的Wato Tachibana贯地谷诗穗梨与任职警队的调查顾问Sara Shelly Futaba竹内结子组成搭档以过人的推理技巧破解一件又一件的悬案
在结尾Wournos警长因不堪忍受超自然力量的折磨而选择「自毁」临死前他叮嘱Nathan接管警长的职位继续保护港湾镇他还告诉Audrey有些人并不希望她回来Audrey向Nathan承认Lucy不是她的母亲而是她本人再世化身Nathan则透露他可以感觉到Audrey的触摸一个自称联邦调查局探员Audrey Parker的女人突然出现要求「Audrey」把事情的来龙去脉说清楚2港湾镇镇长的儿子Chris BrodyJason Priestley将登场亮相他也是一个拥有超自然能力的人与此同时Duke的妻子Evi RyanVinessa Antoine突然回到镇上她似乎有自己的打算 在2首集中Audrey和Nathan发现一种超自然力量将把致命瘟疫散布到港湾镇与此同时Audrey还要面对那个黑头发的「自己」－－她不仅拥有她的名字还拥有她所有的记忆
